The institute's main research topics include:

- atomic physics, laser spectroscopy
- quantum and nonlinear optics, photonics
- quantum information
- matter wave physics
- interaction of radiation with matter
- new solid-state lasers, laser materials and schemes
- growth and characterization of laser and scintillation crystals
- thin film structures for microelectronics and laser technologies
- solid state physics, organic ferromagnetism
- high-temperature superconductivity
- synthesis and characterization of nanomaterials
- scientific instrumentation